{"id":3832,"date":"2023-02-20T16:49:22","date_gmt":"2023-02-20T14:49:22","guid":{"rendered":"https:\/\/marte.i3a.es\/?p=3832"},"modified":"2023-03-17T16:08:06","modified_gmt":"2023-03-17T14:08:06","slug":"eduardo-bolea-fernandez","status":"publish","type":"post","link":"https:\/\/marte.i3a.es\/es\/eduardo-bolea-fernandez\/","title":{"rendered":"Eduardo Bolea Fern\u00e1ndez"},"content":{"rendered":"
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    Investigadores<\/a><\/h3>\n

    Eduardo Bolea Fern\u00e1ndez<\/strong><\/h1>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t<\/ul>\t\t\t\t
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      Tel\u00e9fono:<\/strong> +34 876 553 510<\/p>\n

      Email:<\/strong> ebolea@unizar.es<\/a><\/p>\n

      Direcci\u00f3n:<\/strong> c\/Pedro Cerbuna 12, Universidad de Zaragoza, Facultad de Ciencias, Departamento de Qu\u00edmica Anal\u00edtica \u2013 Zaragoza (Espa\u00f1a)<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>\n\n

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      Eduardo Bolea Fern\u00e1ndez obtuvo su Licenciatura y M\u00e1ster en Qu\u00edmica por la Universidad de Zaragoza, Espa\u00f1a. Llev\u00f3 a cabo su investigaci\u00f3n de doctorado en la Universidad de Gante, B\u00e9lgica, y obtuvo su t\u00edtulo de Doctor en 2017. Su doctorado estaba enfocado en el desarrollo de nuevos m\u00e9todos para el an\u00e1lisis elemental e isot\u00f3pico de ultra-trazas utilizando espectrometr\u00eda de masas-ICP en t\u00e1ndem (ICP-MS\/MS). En octubre de 2017, Eduardo obtuvo una beca de investigaci\u00f3n postdoctoral (BOF-UGent) centrada en el an\u00e1lisis isot\u00f3pico de mercurio de alta precisi\u00f3n utilizando espectrometr\u00eda de masas-ICP multi-colector con el objetivo de descifrar su ciclo biogeoqu\u00edmico. En abril de 2018, gan\u00f3 el Premio Internacional 2018 IUPAC-Solvay para J\u00f3venes Qu\u00edmicos<\/em> entregado a las mejores tesis doctorales en ciencias qu\u00edmicas a nivel mundial. En noviembre de 2019, comenz\u00f3 una beca de investigaci\u00f3n postdoctoral junior (FWO) basada en el desarrollo de nuevos m\u00e9todos anal\u00edticos y su aplicaci\u00f3n en metal\u00f3mica y nanotecnolog\u00eda. En enero de 2022, gan\u00f3 el prestigioso premio \u201cYoung Scientist Winter Conference Award in Plasma Spectrochemistry\u201d por sus contribuciones en este campo. En noviembre de 2022, comenz\u00f3 una beca de investigaci\u00f3n postdoctoral senior (FWO) enfocada en el an\u00e1lisis individual de c\u00e9lulas. En enero de 2023, fue galardonado con un contrato Ram\u00f3n y Cajal (Ministerio de Ciencia e Innovaci\u00f3n, Gobierno de Espa\u00f1a).<\/p>\n

      Hasta ahora, Eduardo es (co-)autor de 39 publicaciones en revistas internacionales y su trabajo ha sido presentado en >50 charlas en conferencias internacionales y workshops.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>

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      39 registros<\/span> «<\/a> ‹<\/a> 1 de 8 ›<\/a> »<\/a> <\/div><\/div>

      2025<\/h3>

      Rua-Ibarz, Ana; Nakadi, Fl\u00e1vio V.; Bolea-Fernandez, Eduardo; Bazo, Antonio; Battistella, Beatrice; Matiushkina, Anna; Resch-Genger, Ute; Abad, Carlos; Resano, Mart\u00edn<\/p>

      Discrete Entity Analysis via Microwave-Induced Nitrogen Plasma\u2013Mass Spectrometry in Single-Event Mode<\/a> Art\u00edculo de revista<\/span> <\/p>

      En: <\/span>Analytical Chemistry, <\/span>vol. 97, <\/span>pp. 24065-24072, <\/span>2025<\/span>, (PMID: 41084806)<\/span>.<\/p>

      Resumen<\/a><\/span> | Enlaces<\/a><\/span> | BibTeX<\/a><\/span><\/p>

      @article{,
      \r\ntitle = {Discrete Entity Analysis via Microwave-Induced Nitrogen Plasma\u2013Mass Spectrometry in Single-Event Mode},
      \r\nauthor = {Ana Rua-Ibarz and Fl\u00e1vio V. Nakadi and Eduardo Bolea-Fernandez and Antonio Bazo and Beatrice Battistella and Anna Matiushkina and Ute Resch-Genger and Carlos Abad and Mart\u00edn Resano},
      \r\nurl = {https:\/\/doi.org\/10.1021\/acs.analchem.5c04341},
      \r\ndoi = {10.1021\/acs.analchem.5c04341},
      \r\nyear  = {2025},
      \r\ndate = {2025-10-14},
      \r\nurldate = {2025-10-14},
      \r\njournal = {Analytical Chemistry},
      \r\nvolume = {97},
      \r\npages = {24065-24072},
      \r\nabstract = {In this work, single-event microwave-induced nitrogen plasma\u2013mass spectrometry (single-event MINP-MS) was evaluated for the first time for the analysis of discrete entities such as nanoparticles, biological cells, and microplastics. Nitrogen (N2) effectively overcomes Ar-based polyatomic interferences, enabling (ultra)trace element determination of Fe and Se using their most abundant isotopes, 56Fe (91.66%) and 80Se (49.82%). Iron oxide nanoparticles (Fe2O3 NPs) ranging from 20 to 70 nm were accurately characterized, with excellent agreement with established sizing techniques, such as transmission electron microscopy (TEM) and dynamic light scattering (DLS). A limit of detection (LoD) of 8.6 ag for Fe\u2500equivalent to an LoDsize of 19 nm for Fe2O3\u2500was achieved, which is significantly lower than recent values reported for high-end quadrupole-based ICP-MS. Selenium nanoparticles (SeNPs) of 150 and 250 nm were also accurately characterized, without the N2-based plasma experiencing issues handling relatively large metallic NPs (linearity, R2 = 0.9994). Se-enriched yeast cells (SELM-1 certified reference material) were successfully analyzed via single-cell MINP-MS using external calibration based on SeNPs and a transport efficiency-independent approach. In addition, 2\u20133 \u03bcm polystyrene (PS) and polytetrafluoroethylene (PTFE) were accurately sized by monitoring 12C+, confirming the method\u2019s suitability for handling micrometer-sized polymeric materials (microplastics). The average duration of individual events (680 \u00b1 160 \u03bcs) suggests that the digestion of individual entities in N2-based plasmas is comparable to that in Ar-based plasmas. These results open new avenues for this instrumentation as an alternative to ICP ionization sources, also in the context of discrete entity analysis.},
      \r\nnote = {PMID: 41084806},
      \r\nkeywords = {},
      \r\npubstate = {published},
      \r\ntppubtype = {article}
      \r\n}
      \r\n<\/pre><\/div>
      Cerrar<\/a><\/p><\/div>
      In this work, single-event microwave-induced nitrogen plasma\u2013mass spectrometry (single-event MINP-MS) was evaluated for the first time for the analysis of discrete entities such as nanoparticles, biological cells, and microplastics. Nitrogen (N2) effectively overcomes Ar-based polyatomic interferences, enabling (ultra)trace element determination of Fe and Se using their most abundant isotopes, 56Fe (91.66%) and 80Se (49.82%). Iron oxide nanoparticles (Fe2O3 NPs) ranging from 20 to 70 nm were accurately characterized, with excellent agreement with established sizing techniques, such as transmission electron microscopy (TEM) and dynamic light scattering (DLS). A limit of detection (LoD) of 8.6 ag for Fe\u2500equivalent to an LoDsize of 19 nm for Fe2O3\u2500was achieved, which is significantly lower than recent values reported for high-end quadrupole-based ICP-MS. Selenium nanoparticles (SeNPs) of 150 and 250 nm were also accurately characterized, without the N2-based plasma experiencing issues handling relatively large metallic NPs (linearity, R2 = 0.9994). Se-enriched yeast cells (SELM-1 certified reference material) were successfully analyzed via single-cell MINP-MS using external calibration based on SeNPs and a transport efficiency-independent approach. In addition, 2\u20133 \u03bcm polystyrene (PS) and polytetrafluoroethylene (PTFE) were accurately sized by monitoring 12C+, confirming the method\u2019s suitability for handling micrometer-sized polymeric materials (microplastics). The average duration of individual events (680 \u00b1 160 \u03bcs) suggests that the digestion of individual entities in N2-based plasmas is comparable to that in Ar-based plasmas. These results open new avenues for this instrumentation as an alternative to ICP ionization sources, also in the context of discrete entity analysis.<\/div>
      Cerrar<\/a><\/p><\/div>